NSEB topic read · 3 min
Read Digoxin Through Ion Gradients
Trace pump inhibition through each ion gradient before predicting cardiac force.
NSEB · Cardiac Physiology · 1 linked question · 100% coverage
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Digoxin and Ion Handling is the central idea in this question pattern. Identify the condition in the stem before applying the method below.
Study deeper: NCERT Biology · Cardiac Physiology
Follow the Na⁺/Ca²⁺ link
Digoxin inhibits Na⁺/K⁺ ATPase, raising intracellular Na⁺. The smaller Na⁺ gradient slows Na⁺/Ca²⁺ exchange, so intracellular Ca²⁺ rises and contractility increases. Choose B.
OlympIQ exam lens
- ✓Na⁺/K⁺ ATPase inhibition raises intracellular Na⁺.
- ✓Less Na⁺ gradient slows Ca²⁺ extrusion.
- ✓Higher intracellular Ca²⁺ increases contractility.
OlympIQ trap
Do not reverse the first ion change: intracellular Na⁺ rises after pump inhibition.
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