Read Hexokinase and Glucokinase
A short NSEB read on hexokinase and glucokinase, followed by the linked original question(s).
Living-system questions are solved by matching a structure or organism to its function, process and stated condition.
Core idea
Hexokinase has a low Km and is active in many tissues even when blood glucose is low, sustaining basal glycolysis. Glucokinase has a higher Km and greater capacity; it is prominent in liver and pancreatic β cells, where it handles abundant glucose after a meal and contributes to glucose sensing. Use both kinetic parameters and tissue distribution to assess statements.
Tissue-specific glucose phosphorylation
Glucokinase has higher Km and functions in liver after meals; hexokinase has lower Km and supports glycolysis in tissues even at fasting glucose. Thus I and III are correct.
OlympIQ exam lens
- ✓Hexokinase has a low Km and is active in many tissues even when blood glucose is low, sustaining basal glycolysis.
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